Fibralign Corporation

Fibralign manufactures a revolutionary type of 3D oriented matrix which mimics the matrices found in human skin and tendons. These nanoscale structures utilize collagen, laminin, fibrin and other biopolymers, specifically engineered for use in cell and tissue engineering applications. Fibralign's multidisciplinary team has developed a proprietary technology and novel production process to provide customized matrices to match research and medical requirements.

Matrix Technology

The extra cellular matrix (ECM) found in the human body provides the scaffold structure for cell attachment. It gives strength and resiliency to skin, bone, cartilage, and tendon and is composed of interwoven biopolymer fibers. Each part of the body has a unique ECM organization optimized for its specific function. A key component of ECM is collagen which is oriented, for example, in a skin-like or tendon-like manner.

Collagen orientation is optimal in a newborn, but degrades over its lifetime. For example, this optimal orientation contributes to skin which can heal with no scarring prior to the first trimester. The Fibralign technology allows collagen matrices which mimic this optimal orientation to be designed into tissue engineered products for improved performance.

Fibralign’s matrices combine commonly used growth enhancement agents along with oriented biopolymers to produce products for a number of medical and life science applications. These applications are based on the improved growth environment for variety of cell cultures and well-accepted relationship between tissue structure and mechanical functions.

Most of the synthetic biomaterials on the market today lack the natural complexity found in the human body and offer only oversimplified versions of ECM. Fibralign's goal is to provide the first interwoven biopolymer matrices that more accurately mimic natural ECM.